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Deep Survival Machines: Fully Parametric Survival Regression and Representation Learning for Censored Data with Competing Risks

About

We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazard of the underlying survival distribution, as required by the Cox-proportional hazard model. By jointly learning deep nonlinear representations of the input covariates, we demonstrate the benefits of our approach when used to estimate survival risks through extensive experimentation on multiple real world datasets with different levels of censoring. We further demonstrate advantages of our model in the competing risks scenario. To the best of our knowledge, this is the first work involving fully parametric estimation of survival times with competing risks in the presence of censoring.

Chirag Nagpal, Xinyu Rachel Li, Artur Dubrawski• 2020

Related benchmarks

TaskDatasetResultRank
Survival PredictionMETABRIC
C-index0.67
21
Survival PredictionSUPPORT
C-index (%)63.7
21
Survival AnalysisSEER (test)
IBS (Primary)0.0613
18
Survival AnalysisFramingham (test)
IBS Primary0.0847
18
Survival AnalysisPBC (test)
IBS (Primary)0.1103
18
Competing Risks Survival AnalysisSynthetic (test)
IBS (Primary)0.175
9
Survival AnalysisSynthetic (test)
IBS (Primary)17.43
9
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