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Deep Survival Machines: Fully Parametric Survival Regression and Representation Learning for Censored Data with Competing Risks

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We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazard of the underlying survival distribution, as required by the Cox-proportional hazard model. By jointly learning deep nonlinear representations of the input covariates, we demonstrate the benefits of our approach when used to estimate survival risks through extensive experimentation on multiple real world datasets with different levels of censoring. We further demonstrate advantages of our model in the competing risks scenario. To the best of our knowledge, this is the first work involving fully parametric estimation of survival times with competing risks in the presence of censoring.

Chirag Nagpal, Xinyu Rachel Li, Artur Dubrawski• 2020

Related benchmarks

TaskDatasetResultRank
Survival AnalysisFLCHAIN
C-idx0.7913
30
Survival PredictionFLCHAIN
IBS0.0981
26
Survival AnalysisPBC
C-index0.8775
26
Survival AnalysisFRAMINGHAM
Time-dependent C-index0.7412
23
Survival AnalysisSUPPORT
Time-dependent C-index0.6656
23
Survival PredictionMETABRIC
C-index0.67
21
Survival PredictionSUPPORT
C-index (%)63.7
21
Survival AnalysisFLCHAIN (test)
Brier Score0.0587
18
Survival AnalysisSUPPORT
C-Index0.9596
18
Survival AnalysisSUPPORT (test)
Brier Score0.0134
18
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