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Curia: A Multi-Modal Foundation Model for Radiology

About

AI-assisted radiological interpretation is based on predominantly narrow, single-task models. This approach is impractical for covering the vast spectrum of imaging modalities, diseases, and radiological findings. Foundation models (FMs) hold the promise of broad generalization across modalities and in low-data settings. However, this potential has remained largely unrealized in radiology. We introduce Curia, a foundation model trained on the entire cross-sectional imaging output of a major hospital over several years, which to our knowledge is the largest such corpus of real-world data-encompassing 150,000 exams (130 TB). On a newly curated 19-task external validation benchmark, Curia accurately identifies organs, detects conditions like brain hemorrhages and myocardial infarctions, and predicts outcomes in tumor staging. Curia meets or surpasses the performance of radiologists and recent foundation models, and exhibits clinically significant emergent properties in cross-modality, and low-data regimes. To accelerate progress, we release our base model's weights at https://huggingface.co/raidium/curia.

Corentin Dancette, Julien Khlaut, Antoine Saporta, Helene Philippe, Elodie Ferreres, Baptiste Callard, Th\'eo Danielou, L\'eo Alberge, L\'eo Machado, Daniel Tordjman, Julie Dupuis, Korentin Le Floch, Jean Du Terrail, Mariam Moshiri, Laurent Dercle, Tom Boeken, Jules Gregory, Maxime Ronot, Fran\c{c}ois Legou, Pascal Roux, Marc Sapoval, Pierre Manceron, Paul H\'erent• 2025

Related benchmarks

TaskDatasetResultRank
Image RegistrationLearn2Reg Abdomen CT-CT (val)
DICE69.2
78
Medical Image SegmentationAMOS Liver 22
DSC97.3
15
Generalist Medical Image AnalysisCuriaBench 3D Track
Average Score86
11
2D Medical Imaging AnalysisCuriaBench 2D Track 1.0 (test)
Average Score87.9
8
2D SegmentationAMOS Left kidney 22
DSC94.5
5
2D SegmentationAMOS Stomach 22
DSC87.6
5
2D SegmentationTotalSegmentator Organs group (standard split)
DSC81.2
5
2D SegmentationTotalSegmentator Vertebrae group (standard)
DSC81.3
5
2D SegmentationTotalSegmentator Cardiac group (standard split)
DSC80.4
5
2D SegmentationTotalSegmentator Musculoskeletal group (standard split)
DSC81.2
5
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