TraCeR: Transformer-Based Competing Risk Analysis with Longitudinal Covariates
About
Survival analysis is a critical tool for modeling time-to-event data. Recent deep learning-based models have reduced various modeling assumptions including proportional hazard and linearity. However, a persistent challenge remains in incorporating longitudinal covariates, with prior work largely focusing on cross-sectional features, and in assessing calibration of these models, with research primarily focusing on discrimination during evaluation. We introduce TraCeR, a transformer-based survival analysis framework for incorporating longitudinal covariates. Based on a factorized self-attention architecture, TraCeR estimates the hazard function from a sequence of measurements, naturally capturing temporal covariate interactions without assumptions about the underlying data-generating process. The framework is inherently designed to handle censored data and competing events. Experiments on multiple real-world datasets demonstrate that TraCeR achieves substantial and statistically significant performance improvements over state-of-the-art methods. Furthermore, our evaluation extends beyond discrimination metrics and assesses model calibration, addressing a key oversight in literature.
Related benchmarks
| Task | Dataset | Result | Rank | |
|---|---|---|---|---|
| Death Prediction | MIMIC IV | Integrated Brier Score (IBS)0.014 | 8 | |
| Death Prediction | PBC2 | IBS0.113 | 8 | |
| Hemorrhage Prediction | MIMIC-III | Integrated Brier Score0.014 | 8 | |
| Infarction Prediction | MIMIC-III | Integrated Brier Score (IBS)0.011 | 8 | |
| Pneumonia Prediction | MIMIC-III | Integrated Brier Score0.005 | 8 | |
| Respiratory Failure Prediction | MIMIC-III | IBS0.049 | 8 | |
| Sepsis Prediction | eICU | IBS0.055 | 8 | |
| Sepsis Prediction | MIMIC IV | IBS0.111 | 8 | |
| Septicemia Prediction | MIMIC-III | Integrated Brier Score (IBS)0.06 | 8 | |
| Survival Analysis (Death) | MIMIC IV | Ctd0.918 | 8 |