Omni-fMRI: A Universal Atlas-Free fMRI Foundation Model
About
Self-supervised fMRI foundation models have shown promising transfer performance, yet most rely on predefined region-level parcellations that discard fine-grained voxel information and introduce atlas-dependent biases. We propose Omni-fMRI, an atlas-free foundation model that operates directly on voxel-level signals. To enable scalable pretraining on 49,497 fMRI sessions across nine datasets, Omni-fMRI introduces a dynamic patching mechanism that substantially reduces computational cost while preserving informative spatial structure. To support reproducibility and fair comparison, we establish a comprehensive benchmark suite spanning 11 datasets and a diverse set of resting-state and task-based fMRI tasks. Experimental results demonstrate that Omni-fMRI consistently outperforms existing foundation models, providing a scalable and reproducible framework for atlas-free brain representation learning. Code and logs are available.
Related benchmarks
| Task | Dataset | Result | Rank | |
|---|---|---|---|---|
| Age regression | SALD | Mean Squared Error (MSE)0.182 | 23 | |
| Gender Classification | ABCD | Accuracy77.01 | 22 | |
| Disease Diagnosis | ADNI MCI | Accuracy63.4 | 19 | |
| Brain Age Prediction | NKI | MSE0.088 | 12 | |
| Gender Classification | BHRC | Accuracy75.86 | 12 | |
| Age regression | ABIDE | MSE0.427 | 12 | |
| Education Classification | NKI | Accuracy68.13 | 11 |