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Foundation Inference Models for Ordinary Differential Equations

About

Ordinary differential equations (ODEs) are central to scientific modelling, but inferring their vector fields from noisy trajectories remains challenging. Current approaches such as symbolic regression, Gaussian process (GP) regression, and Neural ODEs often require complex training pipelines and substantial machine learning expertise, or they depend strongly on system-specific prior knowledge. We propose FIM-ODE, a pretrained Foundation Inference Model that amortises low-dimensional ODE inference by predicting the vector field directly from noisy trajectory data in a single forward pass. We pretrain FIM-ODE on a prior distribution over ODEs with low-degree polynomial vector fields and represent the target field with neural operators. FIM-ODE achieves strong zero-shot performance, matching and often improving upon ODEFormer, a recent pretrained symbolic baseline, across a range of regimes despite using a simpler pretraining prior distribution. Pretraining also provides a strong initialisation for finetuning, enabling fast and stable adaptation that outperforms modern neural and GP baselines without requiring machine learning expertise.

Maximilian Mauel, Johannes R. H\"ubers, David Berghaus, Patrick Seifner, Ramses J. Sanchez• 2026

Related benchmarks

TaskDatasetResultRank
Trajectory reconstructionODEBench v1 (test)
Success Rate (R² > 0.9)84.4
12
Trajectory GeneralizationODEBench v1 (test)
Success Rate (R² > 0.9)32.8
12
Trajectory GeneralizationODEBench
Fraction R2 > 0.932.8
12
ForecastingVDP Task 1: Uniformly Spaced fixed noise seed (test)
MSE0.02
11
ForecastingVDP Task 2 Irregular Times fixed noise seed (test)
MSE0.13
11
ImputationFHN (FitzHugh Nagumo) missing-data regime (test)
MSE0.04
11
Dynamics PredictionCMU MoCap Subject 09 (test)
MSE (short horizon)6.1
9
Dynamics PredictionCMU MoCap Subject 39 (test)
MSE (short)15.56
9
Dynamics PredictionCMU MoCap Subject 35 (test)
MSE (short)6.92
9
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