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Bayesian Meta-Learning with Expert Feedback for Task-Shift Adaptation through Causal Embeddings

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Meta-learning methods perform well on new within-distribution tasks but often fail when adapting to out-of-distribution target tasks, where transfer from source tasks can induce negative transfer. We propose a causally-aware Bayesian meta-learning method, by conditioning task-specific priors on precomputed latent causal task embeddings, enabling transfer based on mechanistic similarity rather than spurious correlations. Our approach explicitly considers realistic deployment settings where access to target-task data is limited, and adaptation relies on noisy (expert-provided) pairwise judgments of causal similarity between source and target tasks. We provide a theoretical analysis showing that conditioning on causal embeddings controls prior mismatch and mitigates negative transfer under task shift. Empirically, we demonstrate reductions in negative transfer and improved out-of-distribution adaptation in both controlled simulations and a large-scale real-world clinical prediction setting for cross-disease transfer, where causal embeddings align with underlying clinical mechanisms.

Lotta M\"akinen, Jorge Lor\'ia, Samuel Kaski• 2026

Related benchmarks

TaskDatasetResultRank
Disease predictionUKBB Task J44 (out-of-distribution)
AUROC0.82
10
Disease predictionUKBB Task J45 (out-of-distribution)
AUROC0.622
10
Disease predictionUKBB Task G45 (out-of-distribution)
AUROC0.673
10
Disease predictionUKBB Task I21 (out-of-distribution)
AUROC0.714
10
Disease Prediction (G45)UK Biobank G45 target tasks 2018
AUPRC0.021
10
Disease Prediction (I21)UK Biobank I21 2018
AUPRC0.045
10
Disease Prediction (J44)UK Biobank J44 2018 (target tasks)
AUPRC12.6
10
Disease Prediction (J45)UK Biobank J45 target tasks 2018
AUPRC3.8
10
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