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Learning Cardiac Latent Representations in Vectorcardiogram Space

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Electrocardiography (ECG) is a cornerstone of cardiac assessment, making the learning of informative ECG representations fundamental to tasks ranging from disease diagnosis to clinical report generation. However, existing methods operate almost exclusively in the observable ECG signal space. In practice, the standard twelve-lead ECG represents multiple projections of the same underlying cardiac electrical activity from different spatial orientations. Therefore, representation learning in the ECG space inevitably introduces substantial redundancy, which may lead to spurious correlations and increased risk of overfitting. To address this and motivated by the Frank vectorcardiogram (VCG) model, we propose learning a unified latent representation of cardiac electrical activity directly in the VCG space. We introduce LVCG, the first general self-supervised representation learning framework designed to operate in this physically grounded latent space. By learning view-invariant latent VCG representations rather than lead-specific artifacts, VCG minimizes redundancy and improves generalization. LVCG generally outperforms ECG-space baselines across tasks, demonstrating enhanced robustness and generalization, especially in domain shift settings.

Bosong Huang, Panzhen Zhao, Zengxiang Li, Patricia Lee, Wei Jin, Alan Wee-Chung Liew, Ming Jin, Shirui Pan• 2026

Related benchmarks

TaskDatasetResultRank
ECG ClassificationPTBXL Super
Macro AUC80.13
136
ECG ClassificationCSN
Macro AUC84.14
51
ECG ClassificationCPSC 2018
AUC84.15
32
ECG ClassificationPTBXL Sub
Macro AUC0.7919
27
ECG ClassificationPTBXL Rhythm
Macro AUC83.94
27
ECG ClassificationPTB-XL Form
AUC71.24
17
Multi-lead reconstructionCPSC 2018 (test)
MSE0.4
10
Multi-lead reconstructionPTB (test)
MSE0.47
10
Diabetes DetectionMIMIC-IV-ECG-Ext-ICD (Diabetes) (test)
AUC67.5
9
Sepsis DetectionMIMIC-IV-ECG-Ext-ICD Sepsis (test)
AUC76.01
9
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