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A Biconvex Formulation for Stable Transport of Mixture Models with a Unique Solution

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Optimal transport (OT) provides a principled framework for mapping between probability distributions. Despite extensive progress, applying OT to large-scale data remains computationally demanding, and the resulting pointwise transport plans are often difficult to interpret. We introduce Optimal Mixture Transport (OMT), a scalable framework that shifts the transport paradigm from individual samples to mixtures of subpopulations, reformulating the transport problem as a strictly biconvex optimization with a unique global minimizer. We further establish theoretical guarantees on the stability of the OMT map, showing that bounded perturbations of the underlying distributions lead to bounded changes in the transport plan. By formulating subpopulations as exponential-family distributions, OMT decouples computational complexity from the sample size, scaling solely with the number of mixture components. We demonstrate the effectiveness and practicality of OMT on a wide range of synthetic benchmarks and real-world datasets, including image data and large-scale single-cell RNA sequencing measurements.

Yeganeh Marghi, Kelly Jin, Uygar S\"umb\"ul• 2026

Related benchmarks

TaskDatasetResultRank
Transport Map Estimationsci-Plex human Belinostat (test)
Average Sinkhorn Divergence (Dε)7.9
5
Transport Map Estimationhuman scRNA-seq Dacinostat sci-Plex (test)
Average Sinkhorn Divergence (Dε)8.1
5
Transport Map Estimationhuman scRNA-seq Givinostat sci-Plex (test)
Average Sinkhorn Divergence (Dε)8.7
5
Transport Map Estimationhuman scRNA-seq Quisinostat sci-Plex (test)
Average Sinkhorn Divergence (Dε)8.7
5
Transport Map Estimationhuman scRNA-seq Hesperadin sci-Plex (test)
Avg Sinkhorn Divergence (Dε)8
5
Spatial gene expression imputationMERFISH mouse brain (target slice)
Slc17a7 Score90
3
Unpaired Image-to-Image TranslationMNIST
FID1.2
3
Unpaired Image-to-Image TranslationCIFAR-10
FID56.1
3
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