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CoralBay: A Self-Supervised CT Foundation Model

About

Self-supervised learning has enabled large-scale pre-training on 2D natural images, producing general-purpose visual representations that transfer effectively across tasks. However, many medical imaging modalities, such as CT scans, are inherently three-dimensional and differ fundamentally from natural images in both structure and semantics. Volumetric modalities capture spatial continuity, organ anatomy, and intensity-based tissue properties (e.g., Hounsfield Units), which are not adequately modeled by 2D pre-training. To bridge this gap, we introduce CoralBay, a self-distillation framework that extends DINO by using a hierarchical 3D Swin backbone and applying self-distillation to concatenated multi-scale features, enabling data-efficient self-supervised learning of rich spatial representations that encode both global semantics and fine-grained local structure. As a result, CoralBay transfers effectively to a wide range of downstream radiological tasks, demonstrating strong and consistent performance across diverse anatomical targets. In addition, we contribute to the open-source \eva framework by introducing a public, reproducible 3D radiology leaderboard that unifies multiple datasets and establishes a standardized benchmark for evaluating volumetric representation learning methods.

Ioannis Gatopoulos, Nicolas K\"anzig, Sebastian Ot\'alora, Fei Tang• 2026

Related benchmarks

TaskDatasetResultRank
Medical Image ClassificationOrganMNIST3D
Accuracy100
44
Medical Image ClassificationNoduleMNIST3D
AUC91
30
ClassificationCC-CCII--
24
Semantic segmentationCHAOS
Dice97
16
Visual SegmentationKiTS23--
14
SegmentationLiTS 17
Dice Score84
9
SegmentationMSD Pancreas
Dice Score73
9
SegmentationBTCV
Dice Score83
9
ClassificationLUNA25
AUROC (Binary)82
8
SegmentationWORD
Dice Score86
8
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