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TRACE: A Temporal Conditional Estimation for Multimodal Time Series Foundation Models

About

Time series foundation models (TS-FMs) aim to learn generalizable temporal representations that can be adapted to a wide range of downstream tasks. In real-world multimodal settings, time series are frequently affected by temporal misalignment and partial modality missingness, where different modalities are observed at heterogeneous time scales or are partially absent. Existing approaches typically rely on naive imputation or masking strategies, which fail to account for cross-modal dependencies and often lead to misaligned or degraded representations. We propose TRACE, a conditional estimation paradigm for multimodal time series foundation model pipelines under missingness and irregular sampling, allowing incomplete target modalities to be systematically inferred from available auxiliary modalities. We evaluate TRACE on diverse multimodal benchmarks spanning healthcare and affective computing, including the MIMIC-IV clinical dataset and the CMU-MOSI and CMU-MOSEI benchmarks for multimodal sentiment analysis. Across a range of downstream prediction tasks and missing-modality settings, TRACE consistently outperforms prior multimodal fusion approaches, demonstrating improved robustness to severe modality missingness and more reliable cross-modal representations.

Ziwen Kan, Yishuo Chen, Kecheng Li, Andrew Wen, Xiaomeng Wang, Liwei Wang, Jihao Duan, Song Wang, Hongfang Liu, Tianlong Chen• 2026

Related benchmarks

TaskDatasetResultRank
Multimodal Sentiment AnalysisCMU-MOSEI (test)
F1 Score86.45
406
Multimodal Sentiment AnalysisCMU-MOSI (test)
F187.04
390
48-hour In-Hospital Mortality (48-IHM)MIMIC IV
AUC83.29
24
Length of Stay (LOS)MIMIC IV
F1 Score77.6
21
Phenotyping (25-label)MIMIC IV
AUROC75
20
Multimodal Clinical PredictionMIMIC IV
AUROC (48h IHM)83.6
6
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