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Identifiability and Estimation for Unlabeled Finite Mixtures under Marginal Independence

About

We study component recovery and mixing-matrix estimation from unlabeled finite mixtures whose observable distributions share the same latent components but have unknown mixing weights. The main identifying signal is marginal independence: each component is assumed to be independent on at least one coordinate pair, but no labels, clean component samples, or mixing weights are observed. We first prove a structural result for product components: under linear independence of the univariate marginals, any independent affine combination of the components must coincide with a single component. We then extend this principle to observable mixtures and show that, under full-rank and no-cancellation conditions, marginally independent affine combinations recover the corresponding latent components. When every component is independent on some coordinate pair, all components are identifiable, and the mixing matrix is recoverable under the stated completion conditions. Finally, we propose a Product-Marginal Maximum Mean Discrepancy (PM-MMD) estimator over affine combinations of the observable mixtures and prove uniform convergence and stability under approximate marginal independence. This framework also separates the empirical roles of the assumptions: irreducibility is, in general, not directly testable from the unlabeled mixtures alone, whereas marginal independence yields a candidate-level diagnostic through held-out PM-MMD. Controlled and flow-cytometry experiments show when marginal independence provides a useful recovery signal. In the reported multi-component comparisons, condition-aware representative selection stabilizes PM-MMD and improves recovery relative to clustering, factorization, and pairwise mixture-proportion baselines using the same unlabeled mixtures.

Takafumi Kanamori, Yushi Hirose, Shohei Yamamoto• 2026

Related benchmarks

TaskDatasetResultRank
Mixing matrix estimationDigits Semi-synthetic
Relative Frobenius Error0.1203
16
Mixture separationgated-pool DLBCL
Relative Frobenius Error0.1078
16
Mixing matrix estimationWine Semi-synthetic
Relative Frobenius Error0.0873
16
Mixture Proportion EstimationDLBCL flow-cytometry raw (two manual-gated cell populations)
Relative Frobenius Error3.92
16
Mixing matrix estimationDLBCL flow-cytometry three-component rho=0.70 (raw gated-pool)
Mean Relative Frobenius Error0.1078
13
Mixing matrix estimationDry Bean-A (Semi-synthetic)
Relative Frobenius Error0.2073
8
Mixing matrix estimationDry Bean B Semi-synthetic
Relative Frobenius Error0.2239
8
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