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TRIAGE: Dialectical Reasoning for Explainable Risk Prediction on Irregularly Sampled Medical Time Series with LLMs

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Clinical early warning systems built on electronic health records, in which clinical observations are recorded as irregularly sampled medical time series (ISMTS), must deliver both calibrated risk scores for patient triage and interpretable rationales that clinicians can verify. Large Language Models (LLMs) have been explored for this task, yet they collapse graded clinical risk into overconfident binary predictions. This risk polarization undermines both calibration and cross-patient comparability. To address this, we propose TRIAGE, a framework that trains an LLM to generate dialectical reasoning over competing clinical outcomes by eliciting outcome-specific rationales. This dialectical formulation mitigates risk polarization, enabling a single LLM to yield continuous risk scores grounded in explicit clinical reasoning. Evaluated on three ISMTS benchmarks, TRIAGE achieves an average AUPRC improvement of 3.3% and reduces calibration error by 81% compared to the competitive baselines. An LLM-as-a-judge assessment further shows that our rationales surpass post-hoc explanations from the baseline by 20% in clinical reasoning quality. The source code is available at https://github.com/HyeongWon-Jang/TRIAGE .

Hyeongwon Jang, Gyouk Chu, Changhun Kim, Joonhyung Park, Hangyul Yoon, Eunho Yang• 2026

Related benchmarks

TaskDatasetResultRank
In-hospital mortality predictionMIMIC-III (test)
AUC0.867
70
In-hospital mortality predictionMIMIC-III--
36
Sepsis PredictionSepsis (test)
AUPRC53.8
22
In-hospital mortality predictionP12 (test)
AUROC87.3
12
In-hospital mortality predictionP12
ECE4
7
Sepsis onset predictionP19
Expected Calibration Error (ECE)0.04
7
Clinical Reasoning Quality EvaluationP12 (200 randomly sampled cases)
Interpretive Summary Score (I)3.429
2
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