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Drug co-lethality prediction on L1000 Transcriptional Signatures (200K pairs)
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0.85
CAL AUC
CAL
0.66696
0.71448
0.762
0.80952
Mar 21, 2026
CAL AUC
CB AUC
Shuffled AUC
Shuffled CB AUC
Updated 2mo ago
Evaluation Results
Method
Method
Links
CAL AUC
CB AUC
Shuffled AUC
Shuffled CB AUC
CAL
Setting=Random neg.
2026.03
0.85
-
0.909
-
CAL
Setting=In-batch neg.
2026.03
0.674
-
-
-
Cosine Baseline (CB)
Setting=In-batch neg.
2026.03
-
0.679
-
-
Cosine Baseline (CB)
Setting=Random neg.
2026.03
-
0.842
-
0.908
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