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Benchmarks
Drug Response Prediction on GDSC2 (10-fold drug-blind CV, leave-one-drug-out CV)
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0.772
All-drug Correlation (r)
Mechanism-stratified training
0.41112
0.50481
0.5985
0.69219
May 20, 2026
All-drug Correlation (r)
Profile Concordance
Within-MoA Correlation (r)
Updated 13d ago
Evaluation Results
Method
Method
Links
All-drug Correlation (r)
Profile Concordance
Within-MoA Correlation (r)
Mechanism-stratified training
MoA class=Mitosis, n=7...
2026.05
0.772
0.713
0.788
Mechanism-stratified training
MoA class=Genome integ...
2026.05
0.742
0.57
0.73
Mechanism-stratified training
MoA class=PI3K/MTOR si...
2026.05
0.61
0.489
0.702
Mechanism-stratified training
MoA class=RTK signalin...
2026.05
0.605
0.454
0.64
Mechanism-stratified training
MoA class=Apoptosis re...
2026.05
0.524
0.331
0.515
Mechanism-stratified training
MoA class=ERK MAPK sig...
2026.05
0.427
0.565
0.723
Mechanism-stratified training
MoA class=EGFR signali...
2026.05
0.425
0.697
0.799
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