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Mutation Fitness Prediction on ProteinGym

89.74AUROC

TriFit

Updated 4d ago

Evaluation Results

Method	Links
TriFit 2026.04		89.74
ESM3 2026.04		76.92
SaProt-650M 2026.04		75.93
GEMME 2026.04		75.65
VESPA 2026.04		75.64
TranceptEVE L 2026.04		75.49
ESM2-650M 2026.04		74.43
ESM-IF1 2026.04		74.42
MSA Transformer (ensemble) 2026.04		74.3
Tranception L 2026.04		74.14
ESM1v (ensemble) 2026.04		73.12
ESM1b 2026.04		72.12
ESM1v 2026.04		71.66
EVmutation 2026.04		71.65
Site Independent 2026.04		69.67
ProteinMPNN 2026.04		65.32