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Protein Variant Effect Prediction on ProteinGym substitution benchmark

0.681Average Spearman Correlation

AUTOSCIENTISTS

Updated 6d ago

Evaluation Results

Method	Links
AUTOSCIENTISTS 2026.05		0.681	0.607
Kermut 2026.05		0.633	0.666
ProteinNPT 2026.05		0.588	0.765
MSA Transformer Embeddings 2026.05		0.562	0.783
Tranception Embeddings 2026.05		0.525	0.849
AIDO Protein-RAG (16B) 2026.04		0.518	-
VenusREM 2026.04		0.518	-
ESM-1v Embeddings 2026.05		0.514	0.848
ProSST (K=2048) 2026.04		0.507	-
S3F-MSA 2026.04		0.496	-
Protriever 2026.04		0.479	-
ESCOTT 2026.04		0.476	-
S3F 2026.04		0.47	-
ProFam (ensemble) 2026.04		0.47	-
PoET (200M) 2026.04		0.47	-
ESM3 open (1.4B) 2026.04		0.466	-
DPLM-Evo 2026.04		0.459	-
GEMME 2026.04		0.455	-
EVE (ensemble) 2026.04		0.439	-
DPLM-Evo 2026.04		0.42	-