Catalytic Activity Prediction on Enzyme

0.58Spearman Correlation

AMPLIFY-120M Baseline

Updated 23d ago

Evaluation Results

Method	Links
AMPLIFY-120M Baseline 2026.05		0.58
AMPLIFY-120M All-pos MLM+JEPA 2026.05		0.571
AMPLIFY-120M MLM-only 2026.05		0.567
AMPLIFY-120M Masked-pos 2026.05		0.557
ESM2-150M MLM-only 2026.05		0.55
ESM2-35M Masked-pos (SGDm) 2026.05		0.549
ESM2-150M All-pos MLM+JEPA 2026.05		0.548
ESM2-150M Baseline 2026.05		0.547
ESM2-150M Masked-pos (run 1) 2026.05		0.547
ESM2-35M Baseline 2026.05		0.544
ESM2-150M Masked-pos (run 2) 2026.05		0.543
ESM2-150M EMA (4h) EMA 2026.05		0.538
ESM2-35M Masked-pos (AdamW) 2026.05		0.533
MLM+JEPA @90k 2026.05		0.526
ESM2-35M MLM-only 2026.05		0.515
Rand-Init-35M MLM-only 2026.05		0.508
ProteinBERT2-150M masked-pos 2026.05		0.506
ProteinBERT2-35M Masked-pos 2026.05		0.494
ProteinBERT2-35M MLM-only 2026.05		0.478
ESM2-35M All-pos MLM+JEPA 2026.05		0.473
Rand-Init-35M Masked-pos 2026.05		0.468
ProteinBERT2-35M All-pos MLM+JEPA 2026.05		0.465
Rand-Init-35M All-pos MLM+JEPA 2026.05		0.462
ESM2-150M rand-init MLM-only 2026.05		0.461
Rand-Init-35M JEPA-only 2026.05		0.46
ProteinBERT2-35M Baseline 2026.05		0.442
JEPA-only @90k 2026.05		0.442
AMPLIFY-120M JEPA-only 2026.05		0.437
Rand-Init-35M Baseline 2026.05		0.432
ESM2-150M JEPA-only 2026.05		0.415
ESM2-35M JEPA-only 2026.05		0.391
ProteinBERT2-35M JEPA-only 2026.05		0.37